Phase 0 / real inference smoke

SimpleFold-100M ran end to end on Apple Silicon

Three engineering targets were predicted with SimpleFold-100M through the local M3 Max server, scored against RCSB PDB references, and saved as auditable artifacts.

Status

successful_prediction

Median lDDT

0.9625

Targets

3 / 3
successful predictions and scores.

Run Boundary

This is a real inference smoke, not a publication-grade benchmark. The target set is deliberately tiny and classic, the recipe is an engineering fixture, and the comparison value is an internal regression value rather than a SimpleFold paper headline metric.

Per-Target Results

TargetpLDDT meanWall clocklDDTTM-scoreRMSD
1L2Y97.5245121.51 s0.96040.66030.43
1CRN91.1615144.14 s0.98650.97070.37
1UBQ88.9500118.22 s0.96250.96500.70

Verdict

The deterministic fixture verdict reports median lDDT 0.9624857567529903 versus fixture value 0.9694790633021089, a relative error of 0.7213468360316005%.

Artifacts

card.json

Machine-readable result card with predictions, scores, validation, and audit count.

Next Gate

The next run should use the public Cloudflare Tunnel path through science.eigenatlas.com, deploy the updated orchestrator, and compare a no-fixture Reader extraction against the fixture recipe.